2 - 8 June 2008
La Martinique

French West Indies

   46^th meeting of The International Association of Forensic Toxicologists
XVI^eme congrés de la Société Française de Toxicologie Analytique
Annual meeting of the Society of Hair Testing
 

COMMERCIAL WORKSHOP INFORMATIONS

Date, time, and location

Thursday, 5 June

 8.30 – 10.00 : sponsored workshops 1 and 2 by  Thermo (room Lafitte) and Roche (room Sapotille)
10.30 – 12.00 : sponsored workshops 3 and 4 by Waters (room Lafitte) and Inverness Medical innovations (room Sapotille)
14.00 – 15.30 : sponsored workshops 5 and 6 by  Applied Biosystems (room Lafitte) and Randox (room Sapotille)

 Friday, 6 June

17.00 ­ 18.30 : sponsored workshops 7 and 8 by Agilent (room Lafitte) and Siemens (room Sapotille)
 

PROGRAM

   
    Thermo Fischer
 Increasing the Productivity of GC-MS and LC-MS Toxicology and Forensic Analysis,
 Workshop Description:  Moving Toxicology and Forensic Science Forward - the effective use of Thermo Scientific products and expertise.
  Talk 1: Utilizing TurboFlow On-Line Sample Preparation and FAIMS for Improved Identification and Quantitation of Drugs of Abuse by LC-MS/MS (Sarah Robinson, Clinical Marketing Specialist, Thermo Fisher Scientific)
  Talk 2: LCMS Toxicology Screening with ToxID Software (Taha Rezai, Clinical and Toxicology Marketing Specialist, Thermo Fisher Scientific)
  Talk 3: Solutions for Routine GC/MS Toxicology Analysis Based on Workflow Oriented Software (Jason Cole, Toxicology Market Manager, Thermo Fisher Scientific)
  Talk 4: Special Guest Speaker
 

 
    Roche Diagnostics
   Title - "The Value of Oral Fluid Drug Testing"
   Description - Oral fluid provides a quick, non-invasive specimen for testing. The objective of this session is to provide an overview of the utility of oral fluid testing from a clinical and laboratory perspective.
   Topics covered include the history, application and advantages of oral fluid as a matrix, and the clinical utilities of oral fluid drug testing.

   This workshop is co-sponsored by Roche Diagnostics and OraSure Technologies Inc and the speakers will likely be company representatives.
 

 
    Waters
 Attend our workshop entitled "Recent Advances in Liquid Chromatography and Mass Spectrometry for Forensic Toxicology". Waters has been working with leading toxicology laboratories to develop applications to meet the challenges of screening and targeted analysis in the forensic laboratory.
 This workshop will bring together forensic toxicologists to share their recent experiences in the analysis of drugs of abuse and improvements these technologies enable in sample throughput, complex sample analysis and sample preparation.
 Please join us to learn more about the implementation of Waters LC/MS solutions along with the scientific and business advantages these solutions deliver.
 

 
     Inverness Medical Innovations

Talk One – Prof. Verstraete : Substitution treatment for opiate addiction: the good, the bad and the ugly.
Talk Two – Prof. Wennig : The growing health issue of Cocaine
Talk Three - Andrew Leibie : Australasian workplace drug testing: Challenge and efficiency of point of care (POC) testing
 
 

 
   Applied Biosystems
   "Advances in the use of LC/MS/MS for Forensic Toxicology Analysis"

    The following workshop will provide an introduction to the technique of LC/MS/MS  and go on to discuss the use of this technology for   the screening and quantification of drugs of abuse and well as the practical considerations when implementing such technology for routine forensic testing.
Talk 1: Dr. Tania Sasaki, Clinical Research and Forensics Technical Marketing Specialist, Applied Biosystems
     Introduction to LC/MS/MS and its use screening and quantitative analysis
Talk 2: Dr. Wolfgang Weinmann, Professor, University of Freiburg, Department of Legal Medicine
     The Implementation and Use of LC/MS/MS for Routine Drug Screening and Quantitation

  
     Randox Laboratories
    
  
Évaluation du dépistage de quatre classes de stupéfiants et des benzodiazépines dans le sang total laqué par l'analyseur Evidence Investigator

Abstract - Evaluation of screening for drugs of abuse and benzodiazepines in forensic blood samples using Evidence InvestigatorTM analyser. Introduction: Semi-quantitative detection of 4 classes of drugs of abuse (opiates, cocaine, cannabinoids and amphetamines) and benzodiazepines in haemolysed whole blood by Evidence Investigatorr analyser has been evaluated in this study. 128 forensic blood samples known to be positive for at least one of these classes by chromatography coupled to mass spectrometric detection were analysed. Results and discussion: Specificity was 79.0 % for amphetamines, 98.1 % for cannabinoids, and 100 % for opiates, cocaine, and benzodiazepines.

Sensitivity was 33.3 % for amphetamines, 78.4 % for benzodiazepines, 93.2 % for cannabinoids, 93.5 % for opiates and 95.2 % for cocaine. 3.9 % of false negatives were observed all classes taken together, due to low concentrations of analytes or due to a bad recognition of some analytes by antibodies. The 4.0 % of false positive results were predominantly observed during amphetamines detection, probably due to presence of biogen amines, as it has previously been reported. An improvement of the technique has been carried out by adding a supplementary wash step during sample preparation. An optimisation of cuto. levels is possible to reduce false negative results during benzodiazepines and cannabinoids detection. Conclusion: This immunoanalytical method enables an efficient detection of opiates, cocaine, cannabinoids and benzodiazepines in forensic blood samples. However a further confirmation and quantification by mass spectrometry techniques remains necessary.
 

   
     Agilent Technologies
     Speaker Agilent : Michelle Moore

     17.15 Welcome with cocktails and food
     17.30 Keynote speaker: “Poisons of the Caribbean”  (Michelle Moore)
     18.00 Q & A
     18.15 informal poster session with Agilent technical specialists
     Open end
     Participants are welcome to join anytime for interesting talks, lecture, food and drinks

  
      Siemens
     "Antibodies: From Structures to Immunoassays"
The speaker will be Dr. William Bedzyk, Principal Scientist, Siemens Healthcare. The workshop will offer a discussion on the function and    structure of antibodies, the various types, specific considerations when producing antibodies to elicit the correct response, and the actual process used to make antibodies followed by examples